Host: Can I get depressed for no reason other than brain chemistry?
Dr. Kim Penberthy: We do know that through your brain chemistry the neurotransmitters in your brain can cause symptoms of depression, but certainly, that's not the only reason. So yes, other factors - environmental factors like stressful work situations or stressful relationships or a loss, a death or a significant loss can influence your symptoms of depression and make them worse.
We also know that some medical conditions can cause symptoms of depression like a thyroid disorder can cause depression. So there are multiple ways that people can become depressed.